TRIM25 Antikörper (Middle Region)
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- Target Alle TRIM25 Antikörper anzeigen
- TRIM25 (Tripartite Motif Containing 25 (TRIM25))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Rind (Kuh), Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TRIM25 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- TPSSGDPGEH DPASTHKSTR PVKKVSKEEK KSKKPPPVPA LPSKLPTFGA
- Homologie
- Cow: 91%, Human: 100%, Pig: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TRIM25. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TRIM25
- Top Product
- Discover our top product TRIM25 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 630 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TRIM25 (Tripartite Motif Containing 25 (TRIM25))
- Andere Bezeichnung
- TRIM25 (TRIM25 Produkte)
- Synonyme
- zgc:55773 antikoerper, MGC130751 antikoerper, EFP antikoerper, RNF147 antikoerper, Z147 antikoerper, ZNF147 antikoerper, AA960166 antikoerper, AL022677 antikoerper, Zfp147 antikoerper, Efp antikoerper, Znf147 antikoerper, E3 ubiquitin/ISG15 ligase TRIM25 antikoerper, tripartite motif containing 25 antikoerper, E3 ubiquitin/ISG15 ligase TRIM25-like L homeolog antikoerper, microRNA 3614 antikoerper, tripartite motif-containing 25 antikoerper, LOC100146440 antikoerper, trim25 antikoerper, LOC100490741.L antikoerper, TRIM25 antikoerper, MIR3614 antikoerper, Trim25 antikoerper
- Hintergrund
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The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.
Alias Symbols: EFP, RNF147, Z147, ZNF147
Protein Interaction Partner: UBC, DDX58, SUMO2, AMFR, UBE2D1, SUMO1, PCNA, USP15, UBA1, RPS27A, RPA1, KIF5B, HSPA1L, HSPA1B, HSPA1A, EEF1A2, ACLY, SUZ12, RNF2, EZH2, BMI1, HECW2, TRIM25, TRIM8, TFG, GRIK2, ESR1, OTUB2, USP39, VCP, WARS, UAP1, UBXN6, UBE2S, UBE2D2, TRAF6, ISG15, UBE2D
Protein Size: 630 - Molekulargewicht
- 71 kDa
- Gen-ID
- 7706
- NCBI Accession
- NM_005082, NP_005073
- UniProt
- Q14258
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