USP22 Antikörper (Middle Region)

Produktnummer ABIN2787647

Produktdetails anti-USP22 Antikörper

Target: USP22 (Ubiquitin Specific Peptidase 22 (USP22))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Maus, Pferd, Hund, Meerschweinchen, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PSSCLVCEMS SLFQEFYSGH RSPHIPYKLL HLVWTHARHL AGYEQQDAHE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against USP22. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human USP22

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 525 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu USP22

Target: USP22 (Ubiquitin Specific Peptidase 22 (USP22))

Andere Bezeichnung: USP22 (USP22 Produkte)

Synonyme: USP3L antikoerper, AI427806 antikoerper, zgc:136342 antikoerper, usp22 antikoerper, usp22 b antikoerper, usp22-B antikoerper, usp22-a antikoerper, usp3l antikoerper, ubiquitin specific peptidase 22 antikoerper, ubiquitin specific peptidase 22 S homeolog antikoerper, USP22 antikoerper, Usp22 antikoerper, usp22 antikoerper, usp22.S antikoerper

Hintergrund: USP22 is a subunit of the SAGA transcriptional cofactor complex. It deubiquitylates histone H2B and is recruited to specific genes by activators like Myc. USP22 is needed for cell cycle progression. It deubiquitylates histone H2A in addition to H2B. Altered mRNA expression is associated with therapy failure and death in patients multiple types of cancer.
Alias Symbols: KIAA1063, USP3L
Protein Interaction Partner: UBC, AASDHPPT, STAT3, TAF10, TADA2A, ATXN7, MYC, KAT2A, TRRAP, TAF9B, HIST1H2BD, TADA3, SUMO1, NFATC2, SIRT1, ATXN7L3, FUBP1, HIST2H2BE, HIST2H2AC, MRPL44, ATXN7L3B, USP27X, KIF7, KLHL23, ATXN7L2, TADA1, CCDC101, TADA2B, ENY2, SUPT20H, TAF5L, SND1, CNOT10
Protein Size: 525

Molekulargewicht: 60 kDa

Gen-ID: 23326

NCBI Accession: NM_015276, NP_056091

UniProt: Q9UPT9