CA1 Antikörper (N-Term)

Produktnummer ABIN2787676

Produktdetails anti-CA1 Antikörper

Target: CA1 (Carbonic Anhydrase I (CA1))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Rind (Kuh), Meerschweinchen, Schwein, Schaf, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ASPDWGYDDK NGPEQWSKLY PIANGNNQSP VDIKTSETKH DTSLKPISVS

Homologie: Cow: 79%, Dog: 86%, Guinea Pig: 79%, Human: 100%, Pig: 100%, Rat: 79%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CA1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 261 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CA1

Target: CA1 (Carbonic Anhydrase I (CA1))

Andere Bezeichnung: CA1 (CA1 Produkte)

Hintergrund: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.
Alias Symbols: Car1, CAB, CA-I
Protein Interaction Partner: TFCP2, HSD17B7, MAPK6,
Protein Size: 261

Molekulargewicht: 29 kDa

Gen-ID: 759

NCBI Accession: NM_001738, NP_001729

UniProt: P00915