FKBP2 Antikörper (N-Term)

Produktnummer ABIN2787694

Produktdetails anti-FKBP2 Antikörper

Target: FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Ziege, Meerschweinchen, Pferd, Rind (Kuh), Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FKBP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RLSWFRVLTV LSICLSAVAT ATGAEGKRKL QIGVKKRVDH CPIKSRKGDV

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FKBP2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FKBP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 142 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FKBP2

Target: FKBP2 (FK506 Binding Protein 2, 13kDa (FKBP2))

Andere Bezeichnung: FKBP2 (FKBP2 Produkte)

Synonyme: FKBP-13 antikoerper, PPIase antikoerper, FKBP12 antikoerper, Fkbp2 antikoerper, 13kDa antikoerper, FKBP-2 antikoerper, mFKBP13 antikoerper, mFKBP2 antikoerper, RGD1560660 antikoerper, zgc:101826 antikoerper, FK506 binding protein 2 antikoerper, FK506 binding protein 1a antikoerper, FK506 binding protein 2 L homeolog antikoerper, FKBP2 antikoerper, Fkbp1a antikoerper, Fkbp2 antikoerper, fkbp2 antikoerper, fkbp2.L antikoerper

Hintergrund: FKBP2 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. This gene has two alternatively spliced transcript variants that encode the same isoform. Multiple polyadenylation sites have been described for this gene, but the full length nature of this gene has not been determined.
Alias Symbols: FKBP-13, PPIase
Protein Interaction Partner: UBQLN1, RAB3C, VAMP2, RAB6A, UBC, BARD1, UBQLN4, PTGES3, RAP2A, MAPK3, ARFGEF1, EPB41L2, BAG6, EPB41, C1QC, ARFGEF2, CDKN2A,
Protein Size: 142

Molekulargewicht: 16 kDa

Gen-ID: 2286

NCBI Accession: NM_004470, NP_004461

UniProt: P26885