WARS Antikörper (N-Term)

Produktnummer ABIN406710

Produktdetails anti-WARS Antikörper

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WARS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EIDSAVKMLV SLKMSYKAAA GEDYKADCPP GNPAPTSNHG PDATEAEEDF

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against WARS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WARS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 471 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu WARS

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Andere Bezeichnung: WARS (WARS Produkte)

Hintergrund: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: GAMMA-2, IFI53, IFP53
Protein Interaction Partner: UBC, SUMO2, CDC34, CALU, ADSL, AARS, CTPS2, HERC4, NT5C2, FKBP9, EHD1, GNPDA1, GTF3C4, USP5, XPNPEP1, RAD23A, TWF1, PCNA, NUCB1, KTN1, GTF2I, CD81, LIG4, TRIM25, GART, APP, ISG15, TERF1, SIRT7, PSMA3, DNMT3B, DCAF13, DDA1, GBAS, CDK2AP2, MDH2, EEF1A1,
Protein Size: 471

Molekulargewicht: 52 kDa

Gen-ID: 7453

NCBI Accession: NM_004184, NP_004175

UniProt: P23381