Thrombopoietin Antikörper (Middle Region)

Produktnummer ABIN2787808

Produktdetails anti-Thrombopoietin Antikörper

Target: Thrombopoietin (THPO)

Bindungsspezifität: Middle Region

Reaktivität: Human, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Thrombopoietin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NLQPGYSPSP THPPTGQYTL FPLPPTLPTP VVQLHPLLPD PSAPTPTPTS

Homologie: Dog: 83%, Human: 100%, Rabbit: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against THPO. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human THPO

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 353 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Thrombopoietin Antikörper (ABIN2787808)

Baker, Gray, Wright, Fitzsimons, Nimmo, Lowry, Mutrie,: "The effect of a pedometer-based community walking intervention "Walking for Wellbeing in the West" on physical activity levels and health outcomes: a 12-week randomized controlled trial." in: The international journal of behavioral nutrition and physical activity, Vol. 5, pp. 44, (2008) (PubMed).

Details zu Thrombopoietin

Target: Thrombopoietin (THPO)

Andere Bezeichnung: THPO (THPO Produkte)

Synonyme: MGDF antikoerper, MKCSF antikoerper, ML antikoerper, MPLLG antikoerper, THCYT1 antikoerper, TPO antikoerper, Mgdf antikoerper, Ml antikoerper, Mpllg antikoerper, Tpo antikoerper, Tpo1 antikoerper, Tpo2 antikoerper, Tpo3 antikoerper, Tpo4 antikoerper, tpo antikoerper, LOC100231762 antikoerper, thrombopoietin antikoerper, THPO antikoerper, Thpo antikoerper, thpo antikoerper

Hintergrund: Megakaryocytopoiesis is the cellular development process that leads to platelet production. THPO is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. THPO is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene.Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC163194, MGDF, MKCSF, ML, MPLLG, TPO
Protein Interaction Partner: APH1A, NUMBL, EP300, MPL,
Protein Size: 353

Molekulargewicht: 35 kDa

Gen-ID: 7066

NCBI Accession: NM_000460, NP_000451

UniProt: P40225

Pathways: JAK-STAT Signalweg, Hormone Activity