BNIP3L/NIX Antikörper (Middle Region)
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- Target Alle BNIP3L/NIX (BNIP3L) Antikörper anzeigen
- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser BNIP3L/NIX Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- CDSPSPQEDG QIMFDVEMHT SRDHSSQSEE EVVEGEKEVE ALKKSADWVS
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Bnip3l. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product BNIP3L Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 218 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
- Andere Bezeichnung
- Bnip3l (BNIP3L Produkte)
- Synonyme
- BNIP3a antikoerper, NIX antikoerper, NIP3 antikoerper, Nix antikoerper, Nip3 antikoerper, C86132 antikoerper, D14Ertd719e antikoerper, Nip3L antikoerper, bnip3l antikoerper, nip3 antikoerper, zgc:110478 antikoerper, bnip3l2 antikoerper, wu:fb52b03 antikoerper, wu:fc02h04 antikoerper, BCL2 interacting protein 3 like antikoerper, BCL2 interacting protein 3 antikoerper, BCL2/adenovirus E1B interacting protein 3 antikoerper, BCL2/adenovirus E1B interacting protein 3-like antikoerper, BCL2/adenovirus E1B interacting protein 3-like b antikoerper, BCL2/adenovirus E1B interacting protein 3-like a antikoerper, BNIP3L antikoerper, BNIP3 antikoerper, Bnip3l antikoerper, Bnip3 antikoerper, bnip3lb antikoerper, bnip3la antikoerper
- Hintergrund
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Bnip3l induces apoptosis. It interacts with viral and cellular anti-apoptosis proteins. It can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. It inhibits apoptosis induced by BNIP3. It is involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. Bnip3l may function as a tumor suppressor.
Alias Symbols: C86132, D14Ertd719e, Nip3L, Nix
Protein Size: 218 - Molekulargewicht
- 24 kDa
- Gen-ID
- 12177
- NCBI Accession
- NM_009761, NP_033891
- UniProt
- Q9Z2F7
- Pathways
- Autophagie
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