DRAM Antikörper (N-Term)

Produktnummer ABIN2787866

Produktdetails anti-DRAM Antikörper

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TMYTRYKIVQ KQNQTCYFST PVFNLVSLVL GLVGCFGMGI VANFQELAVP

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against DRAM. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DRAM

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 238 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DRAM

Target: DRAM (DRAM1) (DNA-Damage Regulated Autophagy Modulator 1 (DRAM1))

Andere Bezeichnung: DRAM (DRAM1 Produkte)

Synonyme: DRAM1 antikoerper, DRAM antikoerper, 1200002N14Rik antikoerper, Dram antikoerper, dram antikoerper, DNA damage regulated autophagy modulator 1 antikoerper, DNA-damage regulated autophagy modulator 1 antikoerper, DNA damage regulated autophagy modulator 1 L homeolog antikoerper, DRAM1 antikoerper, Dram1 antikoerper, dram1.L antikoerper

Hintergrund: This gene is regulated as part of the p53 tumor suppressor pathway. The gene encodes a lysosomal membrane protein that is required for the induction of autophagy by the pathway. Decreased transcriptional expression of this gene is associated with various tumors. This gene has a pseudogene on chromosome 4.
Alias Symbols: DRAM, FLJ11259
Protein Interaction Partner: C1orf21, APP,
Protein Size: 238

Molekulargewicht: 26 kDa

Gen-ID: 55332

NCBI Accession: NM_018370, NP_060840

UniProt: Q8N682