PSMF1 Antikörper (Middle Region)
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- Target Alle PSMF1 Antikörper anzeigen
- PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PSMF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- DYIDAEHLGD FHRTYKNSEE LRSRIVSGII TPIHEQWEKA NVSSPHREFP
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PSMF1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PSMF1
- Top Product
- Discover our top product PSMF1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 271 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))
- Andere Bezeichnung
- PSMF1 (PSMF1 Produkte)
- Synonyme
- PI31 antikoerper, AW048666 antikoerper, BC012260 antikoerper, zgc:92785 antikoerper, proteasome inhibitor subunit 1 antikoerper, proteasome (prosome, macropain) inhibitor subunit 1 antikoerper, PSMF1 antikoerper, Psmf1 antikoerper, psmf1 antikoerper
- Hintergrund
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
Alias Symbols: PI31
Protein Interaction Partner: FBXO7, SHFM1, UBC, BEND7, RHOXF2, KHDRBS3, PAK7, LDOC1, RBFOX2, PSMA7, DVL3, RALYL, RBFOX1, QKI, CD2BP2, CUL1, PSMA2, MIEF2, CCDC85B, RNF126, PDLIM7, HOOK2, NUDT21, CTBP2, TRAF2, MAGEA11, RBMX,
Protein Size: 271 - Molekulargewicht
- 30 kDa
- Gen-ID
- 9491
- NCBI Accession
- NM_006814, NP_006805
- UniProt
- Q92530
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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