TIMP2 Antikörper (N-Term)
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- Target Alle TIMP2 Antikörper anzeigen
- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Ratte, Maus, Rind (Kuh), Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen, Hund, Pferd, Schaf
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TIMP2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- NADVVIRAKA VSEKEVDSGN DIYGNPIKRI QYEIKQIKMF KGPEKDIEFI
- Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Sheep: 93%, Zebrafish: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against TIMP2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human TIMP2
- Top Product
- Discover our top product TIMP2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 220 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
- Andere Bezeichnung
- TIMP2 (TIMP2 Produkte)
- Synonyme
- CSC-21K antikoerper, DDC8 antikoerper, timp2l antikoerper, zgc:65967 antikoerper, zgc:85799 antikoerper, D11Bwg1104e antikoerper, Timp-2 antikoerper, TIMP-2 antikoerper, etID32613.12 antikoerper, fa96h09 antikoerper, timp2 antikoerper, wu:fa96h09 antikoerper, zgc:136726 antikoerper, TIMP metallopeptidase inhibitor 2 antikoerper, TIMP metallopeptidase inhibitor 2b antikoerper, tissue inhibitor of metalloproteinase 2 antikoerper, TIMP metallopeptidase inhibitor 2a antikoerper, TIMP metallopeptidase inhibitor 2 L homeolog antikoerper, TIMP2 antikoerper, timp2b antikoerper, Timp2 antikoerper, timp2a antikoerper, timp2.L antikoerper
- Hintergrund
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This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
Alias Symbols: CSC-21K, Metalloproteinase inhibitor 2, TIMP2, TIMP metallopeptidase inhibitor 2, Tissue inhibitor of metalloproteinases 2, Timp2
Protein Interaction Partner: BAG3, ITGA3, MMP14, ITGB1, MMP2, MMP8, SNCG, PSMA7,
Protein Size: 220 - Molekulargewicht
- 22 kDa
- Gen-ID
- 7077
- NCBI Accession
- NM_003255, NP_003246
- UniProt
- P16035
- Pathways
- cAMP Metabolic Process
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