RECK Antikörper (Middle Region)
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- Target Alle RECK Antikörper anzeigen
- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RECK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SCIVGGKRKS HGTSFTIDCN VCSCFAGNLV CSTRLCLSEH SSDDDRRTFT
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Reck. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product RECK Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 971 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RECK (Reversion-Inducing-Cysteine-Rich Protein with Kazal Motifs (RECK))
- Andere Bezeichnung
- Reck (RECK Produkte)
- Synonyme
- ST15 antikoerper, St15 antikoerper, mRECK antikoerper, reversion inducing cysteine rich protein with kazal motifs antikoerper, reversion-inducing-cysteine-rich protein with kazal motifs antikoerper, RECK antikoerper, Reck antikoerper
- Hintergrund
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Reck negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. It appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.
Alias Symbols: MGC169689, St15, mRECK
Protein Size: 971 - Molekulargewicht
- 104 kDa
- Gen-ID
- 53614
- NCBI Accession
- NM_016678, NP_057887
- UniProt
- Q9Z0J1
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