USP10 Antikörper (C-Term)
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- Target Alle USP10 Antikörper anzeigen
- USP10 (Ubiquitin Specific Peptidase 10 (USP10))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser USP10 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- RDIRPGAAFE PTYIYRLLTV IKSSLSEKGR QEDAEEYLGF ILNGLHEEML
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Usp10. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product USP10 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 794 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- USP10 (Ubiquitin Specific Peptidase 10 (USP10))
- Andere Bezeichnung
- Usp10 (USP10 Produkte)
- Synonyme
- T4F9.30 antikoerper, T4F9_30 antikoerper, ubiquitin-specific protease 9 antikoerper, ubpo antikoerper, USP10 antikoerper, id:ibd1190 antikoerper, wu:fc19h08 antikoerper, wu:fc76g05 antikoerper, wu:fi11g01 antikoerper, UBPO antikoerper, 2610014N07Rik antikoerper, Uchrp antikoerper, mKIAA0190 antikoerper, usp10-A antikoerper, ubiquitin specific peptidase 10 antikoerper, universal stress protein UspA antikoerper, ubiquitin-specific protease 9 antikoerper, ubiquitin carboxyl-terminal hydrolase 10 antikoerper, ubiquitin specific peptidase 10 S homeolog antikoerper, USP10 antikoerper, RR_RS14970 antikoerper, UBP9 antikoerper, PTRG_07201 antikoerper, MGYG_06403 antikoerper, usp10 antikoerper, Usp10 antikoerper, usp10.S antikoerper
- Hintergrund
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Usp10 is a hydrolase that can remove conjugated ubiquitin from target proteins such as p53/TP53, SNX3 and CFTR. It acts as an essential regulator of p53/TP53 stability: in unstressed cells, specifically deubiquitinates p53/TP53 in the cytoplasm, leading to counteract MDM2 action and stabilize p53/TP53. Following DNA damage, translocates to the nucleus and deubiquitinates p53/TP53, leading to regulate the p53/TP53-dependent DNA damage response. Usp10 does not deubiquitinate MDM2 and deubiquitinates CFTR in early endosomes, enhancing its endocytic recycling.
Alias Symbols: MGC124997
Protein Size: 794 - Molekulargewicht
- 87 kDa
- Gen-ID
- 307905
- NCBI Accession
- NM_001034146, NP_001029318
- UniProt
- Q3KR59
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