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COPS6 Antikörper (Middle Region)

COPS6 Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2788037
  • Target Alle COPS6 Antikörper anzeigen
    COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))
    Bindungsspezifität
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 35
    • 19
    • 19
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)
    Wirt
    • 31
    • 4
    Kaninchen
    Klonalität
    • 32
    • 3
    Polyklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser COPS6 Antikörper ist unkonjugiert
    Applikation
    • 25
    • 13
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    DHVARMTATG SGENSTVAEH LIAQHSAIKM LHSRVKLILE YVKASEAGEV
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Produktmerkmale
    This is a rabbit polyclonal antibody against COPS6. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human COPS6
    Top Product
    Discover our top product COPS6 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 327 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Pick, Golan, Zimbler, Guo, Sharaby, Tsuge, Hofmann, Wei: "The minimal deneddylase core of the COP9 signalosome excludes the Csn6 MPN- domain." in: PLoS ONE, Vol. 7, Issue 8, pp. e43980, (2012) (PubMed).

  • Target
    COPS6 (COP9 Signalosome Complex Subunit 6 (COPS6))
    Andere Bezeichnung
    COPS6 (COPS6 Produkte)
    Synonyme
    CG6932 antikoerper, CH6 antikoerper, Csn6 antikoerper, Dch6 antikoerper, Dmel\\CG6932 antikoerper, zgc:112075 antikoerper, Sgn3 antikoerper, VIP/MOV34 antikoerper, CSN6 antikoerper, MOV34-34KD antikoerper, COP9 signalosome subunit 6 antikoerper, COP-9 SigNalosome subunit antikoerper, COPS6 antikoerper, Cops6 antikoerper, CSN6 antikoerper, cops6 antikoerper, csn-6 antikoerper
    Hintergrund
    The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein belongs to translation initiation factor 3 (eIF3) superfamily. It is involved in the regulation of cell cycle and likely to be a cellular cofactor for HIV-1 accessory gene product Vpr.
    Alias Symbols: CSN6, MOV34-34KD
    Protein Interaction Partner: NEDD8, CUL1, UBC, COPS5, GPS1, SUMO1, POP7, COPS7B, COPS7A, CUL4B, USP7, COPS4, FBXO6, FBXW4, IGHV3OR15-7, vpr, TP63, RFWD2, SFN, IRF5, COPS8, COPS2, COPS3, DDB2, DDB1, ERCC8, TOR1AIP2, LRR1, RBX1, VPRBP, LRRC14, CUL2, CUL3, CUL4A, CUL5, TCEB2, TCEB1, SKP
    Protein Size: 327
    Molekulargewicht
    36 kDa
    Gen-ID
    10980
    NCBI Accession
    NM_006833, NP_006824
    UniProt
    Q7L5N1
    Pathways
    Zellzyklus
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