CLTA Antikörper (C-Term)

Produktnummer ABIN2788075

Produktdetails anti-CLTA Antikörper

Target: CLTA (Clathrin, Light Chain A (CLTA))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLTA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KELEEWYARQ DEQLQKTKAN NRAAEEAFVN DIDESSPGTE WERVARLCDF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against CLTA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLTA

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 218 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CLTA

Target: CLTA (Clathrin, Light Chain A (CLTA))

Andere Bezeichnung: CLTA (CLTA Produkte)

Hintergrund: Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 8 and 12.
Alias Symbols: LCA
Protein Interaction Partner: TP53, UBC, EGFR, PAN2, MYBL2, VCAM1, RGS2, ITGA4, FN1, CFTR, VCP, MAD2L2, SYNJ1, COPS5, CUL3, ARRB2, ARRB1, MAP1LC3B, TNK2, HSPA8, MAP1LC3A, STAMBP, HIP1R, HIP1, CLTC,
Protein Size: 218

Molekulargewicht: 24 kDa

Gen-ID: 1211

NCBI Accession: NM_001833, NP_001824

UniProt: P09496

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation