GRM7 Antikörper (C-Term)
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- Target Alle GRM7 Antikörper anzeigen
- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Ratte, Maus, Hund, Kaninchen, Rind (Kuh), Pferd, Zebrafisch (Danio rerio), Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GRM7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- HPELNVQKRK RSFKAVVTAA TMSSRLSHKP SDRPNGEAKT ELCENVDPNS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against GRM7. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human GRM7
- Top Product
- Discover our top product GRM7 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 915 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))
- Andere Bezeichnung
- GRM7 (GRM7 Produkte)
- Synonyme
- MGLUR7 antikoerper, GLUR7 antikoerper, GPRC1G antikoerper, MGLU7 antikoerper, 6330570A01Rik antikoerper, BB176677 antikoerper, C030018L03 antikoerper, E130018M02Rik antikoerper, Gpr1g antikoerper, Gprc1g antikoerper, mGluR7 antikoerper, glutamate metabotropic receptor 7 antikoerper, glutamate receptor, metabotropic 7 antikoerper, GRM7 antikoerper, Grm7 antikoerper
- Hintergrund
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L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ40498, GLUR7, GPRC1G, MGLU7, MGLUR7
Protein Interaction Partner: UBC, PICK1, TUBA8, TUBA1B, TUBA1A, TUBA3C, GNAQ, GRIPAP1, FLNA, TUBA4A, CALM3, CALM1, PRKCA, GRIP1, SDCBP,
Protein Size: 915 - Molekulargewicht
- 99 kDa
- Gen-ID
- 2917
- NCBI Accession
- NM_000844, NP_000835
- UniProt
- Q14831
- Pathways
- Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour
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