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MANF Antikörper (C-Term)

MANF Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2788136
  • Target Alle MANF Antikörper anzeigen
    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
    Bindungsspezifität
    • 8
    • 7
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 47
    • 20
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)
    Wirt
    • 38
    • 8
    • 1
    Kaninchen
    Klonalität
    • 41
    • 6
    Polyklonal
    Konjugat
    • 28
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MANF Antikörper ist unkonjugiert
    Applikation
    • 39
    • 24
    • 10
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    Western Blotting (WB)
    Sequenz
    EKICEKLKKK DSQICELKYD KQIDLSTVDL KKLRVKELKK ILDDWGETCK
    Homologie
    Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against MANF. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human MANF
    Top Product
    Discover our top product MANF Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 185 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    MANF (Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF))
    Andere Bezeichnung
    MANF (MANF Produkte)
    Synonyme
    ARMET antikoerper, ARP antikoerper, 3230402M22Rik antikoerper, AA407711 antikoerper, AA408789 antikoerper, AA673178 antikoerper, Armet antikoerper, D17914 antikoerper, D18Mgi17 antikoerper, MANF antikoerper, RBM15B antikoerper, ARP-like antikoerper, CG7013 antikoerper, DmMANF antikoerper, Dmel\\CG7013 antikoerper, anon-EST:ParkEST188 antikoerper, arp antikoerper, armet antikoerper, im:6909481 antikoerper, zgc:153327 antikoerper, manf antikoerper, mesencephalic astrocyte derived neurotrophic factor antikoerper, mesencephalic astrocyte-derived neurotrophic factor antikoerper, RNA binding motif protein 15B antikoerper, Mesencephalic astrocyte-derived neurotrophic factor antikoerper, mesencephalic astrocyte-derived neurotrophic factor S homeolog antikoerper, MANF antikoerper, Manf antikoerper, RBM15B antikoerper, manf antikoerper, manf.S antikoerper
    Hintergrund
    MANF is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of MANF gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors, however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
    Alias Symbols: ARMET, ARP, MGC142148, MGC142150
    Protein Interaction Partner: UBC, MDM2,
    Protein Size: 185
    Molekulargewicht
    21 kDa
    Gen-ID
    7873
    NCBI Accession
    NM_006010, NP_006001
    UniProt
    A8K878
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