RASSF1 Antikörper (C-Term)
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- Target Alle RASSF1 Antikörper anzeigen
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Schaf, Zebrafisch (Danio rerio), Meerschweinchen, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser RASSF1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LAGPSDKALS FVLKENDSGE VNWDAFSMPE LHNFLRILQR EEEEHLRQIL
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 85%
- Produktmerkmale
- This is a rabbit polyclonal antibody against RASSF1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human RASSF1
- Top Product
- Discover our top product RASSF1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 270 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))
- Andere Bezeichnung
- RASSF1 (RASSF1 Produkte)
- Synonyme
- RASSF1 antikoerper, zgc:92505 antikoerper, wu:fc17f02 antikoerper, zgc:112224 antikoerper, 123F2 antikoerper, NORE2A antikoerper, RASSF1A antikoerper, RDA32 antikoerper, REH3P21 antikoerper, AA536941 antikoerper, AU044980 antikoerper, Rassf1A antikoerper, Rassf1B antikoerper, Rassf1C antikoerper, NPR2-like, GATOR1 complex subunit antikoerper, Ras association (RalGDS/AF-6) domain family 1 antikoerper, Ras association domain family member 1 antikoerper, putative rassf1 antikoerper, Ras association domain family member 1 L homeolog antikoerper, Ras association (RalGDS/AF-6) domain family member 1 antikoerper, NPRL2 antikoerper, rassf1 antikoerper, RASSF1 antikoerper, Smp_157340 antikoerper, rassf1.L antikoerper, Rassf1 antikoerper
- Hintergrund
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This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Seven alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Alias Symbols: 123F2, NORE2A, RASSF1A, RDA32, REH3P21
Protein Interaction Partner: FBXW11, MDM2, DAXX, SUV39H2, KDM1A, SUV39H1, STK4, STK3, CDC20, SAV1, MAST2, HUWE1, LATS1, BTRC, UBC, ID1, GSK3B, C7orf25, C8orf33, KCNE3, CUL4A, DDB1, Rassf1, SKP2, AURKB, AURKA, SKP1, CUL1, NUDT10, MOAP1, CNKSR1, MAP1S, EXOSC8, RASSF5, TNFRSF10A, E4F1,
Protein Size: 270 - Molekulargewicht
- 30 kDa
- Gen-ID
- 11186
- NCBI Accession
- NM_170713, NP_733831
- UniProt
- Q9NS23
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