MAGE-Like 2 Antikörper (N-Term)

Produktnummer ABIN2788252

Produktdetails anti-MAGE-Like 2 Antikörper

Target: MAGE-Like 2 (MAGEL2)

Bindungsspezifität: N-Term

Reaktivität: Human, Rind (Kuh), Hund, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAGE-Like 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MQGLFYRPQG SSKERRTSSK ERRAPSKDRM IFAATFCAPK AVSAARAHLP

Homologie: Cow: 83%, Dog: 100%, Human: 100%, Pig: 88%, Rabbit: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MAGEL2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MAGEL2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 529 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MAGE-Like 2

Target: MAGE-Like 2 (MAGEL2)

Andere Bezeichnung: MAGEL2 (MAGEL2 Produkte)

Synonyme: NDNL1 antikoerper, nM15 antikoerper, MAGEL2 antikoerper, Mage-l2 antikoerper, ns7 antikoerper, MAGE family member L2 antikoerper, melanoma antigen, family L, 2 antikoerper, MAGEL2 antikoerper, Magel2 antikoerper

Hintergrund: Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS.
Alias Symbols: NDNL1, nM15
Protein Interaction Partner: VPS35, VPS26A, USP7, TRIM27, UBC,
Protein Size: 529

Molekulargewicht: 58 kDa

Gen-ID: 54551

NCBI Accession: NM_019066

UniProt: Q9UJ55