AP1B1 Antikörper (C-Term)

Produktnummer ABIN2788289

Produktdetails anti-AP1B1 Antikörper

Target: AP1B1 (Adaptor-Related Protein Complex 1, beta 1 Subunit (AP1B1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AP1B1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KLFLKKPTET QELVQQVLSL ATQDSDNPDL RDRGYIYWRL LSTDPVAAKE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against AP1B1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AP1B1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 949 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AP1B1

Target: AP1B1 (Adaptor-Related Protein Complex 1, beta 1 Subunit (AP1B1))

Andere Bezeichnung: AP1B1 (AP1B1 Produkte)

Hintergrund: Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants.
Alias Symbols: ADTB1, AP105A, BAM22, CLAPB2
Protein Interaction Partner: UBC, EGFR, RPA3, RPA2, RPA1, TRMT61A, DIABLO, INTS9, TBC1D2, TRIP10, ABCE1, PPP6R3, NTRK2, AP1G1, VCP, BARD1, AP1M1, AP1S2, AP1S1, EPS15, AP2M1, EPN1, SNAP91, CLINT1, COPS5, CUL3, SHBG, CDK2, SIRT7, SNCA, ATF7IP, KIF13A, ATM, AP1M2, PIP5K1C, BUB1B, BUB1,
Protein Size: 949

Molekulargewicht: 104 kDa

Gen-ID: 162

NCBI Accession: NM_001127, NP_001118

UniProt: Q10567