CMA1 Antikörper (C-Term)
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- Target Alle CMA1 Antikörper anzeigen
- CMA1 (Chymase 1, Mast Cell (CMA1))
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Bindungsspezifität
- C-Term
- Reaktivität
- Human, Maus, Ratte, Kaninchen, Schaf, Rind (Kuh), Hund, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CMA1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- EVKLRLMDPQ ACSHFRDFDH NLQLCVGNPR KTKSAFKGDS GGPLLCAGVA
- Homologie
- Cow: 86%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Sheep: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CMA1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CMA1
- Top Product
- Discover our top product CMA1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 247 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CMA1 (Chymase 1, Mast Cell (CMA1))
- Andere Bezeichnung
- CMA1 (CMA1 Produkte)
- Synonyme
- CYH antikoerper, MCT1 antikoerper, chymase antikoerper, MMCP-5 antikoerper, Mcp-5 antikoerper, Mcp5 antikoerper, Mcpt5 antikoerper, MCP3P antikoerper, CMA1 antikoerper, Chymase antikoerper, chymase 1 antikoerper, chymase 1, mast cell antikoerper, chymase-like antikoerper, CMA1 antikoerper, Cma1 antikoerper, LOC100008644 antikoerper
- Hintergrund
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CMA1 is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies.
Alias Symbols: CYH, MCT1, MGC119890, MGC119891, chymase
Protein Interaction Partner: FYN, IL1B, EDN2, EDN1, KITLG, PFN1, EDN3, MMP1, SERPINA3, AGT,
Protein Size: 247 - Molekulargewicht
- 27 kDa
- Gen-ID
- 1215
- NCBI Accession
- NM_001836, NP_001827
- UniProt
- P23946
- Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
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