Factor VIII Antikörper (C-Term)
-
- Target Alle Factor VIII (F8) Antikörper anzeigen
- Factor VIII (F8) (Coagulation Factor VIII (F8))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human, Hund, Kaninchen, Rind (Kuh), Schaf, Pferd
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser Factor VIII Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- IMVTFRNQAS RPYSFYSSLI SYEEDQRQGA EPRKNFVKPN ETKTYFWKVQ
- Homologie
- Cow: 86%, Dog: 77%, Horse: 93%, Human: 100%, Rabbit: 86%, Sheep: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against F8. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human F8
- Top Product
- Discover our top product F8 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 2351 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- Factor VIII (F8) (Coagulation Factor VIII (F8))
- Andere Bezeichnung
- F8 (F8 Produkte)
- Synonyme
- fb61d02 antikoerper, wu:fb61d02 antikoerper, Cf-8 antikoerper, Cf8 antikoerper, FVIII antikoerper, AHF antikoerper, DXS1253E antikoerper, F8B antikoerper, F8C antikoerper, HEMA antikoerper, coagulation factor VIIi antikoerper, coagulation factor VIII antikoerper, coagulation factor VIII, procoagulant component antikoerper, f7i antikoerper, F8 antikoerper
- Hintergrund
-
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder.
Alias Symbols: AHF, DXS1253E, F8B, F8C, FVIII, HEMA
Protein Interaction Partner: UBQLN1, GGA1, MCFD2, PHYH, LMAN1, F9, F10, VWF, F2, PROS1, PROC, HSPA5, CANX, CALR, ASGR2, LRP1,
Protein Size: 2351 - Molekulargewicht
- 79 kDa
- Gen-ID
- 2157
- NCBI Accession
- NM_000132, NP_000123
- UniProt
- P00451
-