CYP3A5 Antikörper (N-Term)
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- Target Alle CYP3A5 Antikörper anzeigen
- CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Schwein, Schaf, Hund, Meerschweinchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYP3A5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- AITDPDVIRT VLVKECYSVF TNRRSLGPVG FMKSAISLAE DEEWKRIRSL
- Homologie
- Cow: 79%, Dog: 91%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 82%, Pig: 93%, Rat: 79%, Sheep: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CYP3A5. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CYP3A5
- Top Product
- Discover our top product CYP3A5 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 502 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CYP3A5 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))
- Andere Bezeichnung
- CYP3A5 (CYP3A5 Produkte)
- Synonyme
- CP35 antikoerper, CYPIIIA5 antikoerper, P450PCN3 antikoerper, PCN3 antikoerper, cytochrome P450 family 3 subfamily A member 5 antikoerper, CYP3A5 antikoerper
- Hintergrund
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This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene.
Alias Symbols: CP35, P450PCN3, PCN3, CYPIIIA5
Protein Interaction Partner: RDH13, ATOH8, ETV5,
Protein Size: 502 - Molekulargewicht
- 57 kDa
- Gen-ID
- 1577
- NCBI Accession
- NM_000777, NP_000768
- UniProt
- P51589
- Pathways
- Steroid Hormone Biosynthesis
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