ST5 Antikörper (Middle Region)
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- Target Alle ST5 Antikörper anzeigen
- ST5 (Suppression of Tumorigenicity 5 (ST5))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Hund
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ST5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- VPKPKRTFEY EADKNPKSKP SNGLPPSPTP AAPPPLPSTP APPVTRRPKK
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ST5. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human ST5
- Top Product
- Discover our top product ST5 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 1137 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ST5 (Suppression of Tumorigenicity 5 (ST5))
- Andere Bezeichnung
- ST5 (ST5 Produkte)
- Synonyme
- zgc:91902 antikoerper, wu:fc11b09 antikoerper, si:ch211-208c6.1 antikoerper, ST5 antikoerper, DKFZp459D1230 antikoerper, hts1 antikoerper, p126 antikoerper, dennd2b antikoerper, DENND2B antikoerper, HTS1 antikoerper, 2010004M01Rik antikoerper, 2610305K15Rik antikoerper, suppression of tumorigenicity 5 antikoerper, st5 antikoerper, ST5 antikoerper, St5 antikoerper
- Hintergrund
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This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
Alias Symbols: DENND2B, HTS1, MGC33090, p126
Protein Interaction Partner: SMAD2, UBC, ABL1, SFN,
Protein Size: 1137 - Molekulargewicht
- 126 kDa
- Gen-ID
- 6764
- NCBI Accession
- NM_005418, NP_005409
- UniProt
- P78524
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