Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

TCHP Antikörper (C-Term)

TCHP Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2788476
  • Target Alle TCHP Antikörper anzeigen
    TCHP (Trichoplein, Keratin Filament Binding (TCHP))
    Bindungsspezifität
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    C-Term
    Reaktivität
    • 30
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae
    Wirt
    • 29
    Kaninchen
    Klonalität
    • 29
    Polyklonal
    Konjugat
    • 10
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TCHP Antikörper ist unkonjugiert
    Applikation
    • 18
    • 18
    • 14
    • 13
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    IQEKIEQNRR AQEESLKHRE QLIRNLEEVR ELARREKEES EKLKSARKQE
    Homologie
    Cow: 100%, Dog: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Yeast: 91%
    Produktmerkmale
    This is a rabbit polyclonal antibody against TCHP. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human TCHP
    Top Product
    Discover our top product TCHP Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 498 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Wong, Vaz, Lee, Zhao, Luo, Archer, Preiss, Tanavde, Vardy: "Embryonic Stem Cells Exhibit mRNA Isoform Specific Translational Regulation." in: PLoS ONE, Vol. 11, Issue 1, pp. e0143235, (2016) (PubMed).

  • Target
    TCHP (Trichoplein, Keratin Filament Binding (TCHP))
    Andere Bezeichnung
    TCHP (TCHP Produkte)
    Synonyme
    TpMs antikoerper, A930031F18Rik antikoerper, AV279199 antikoerper, RGD1310813 antikoerper, zgc:136634 antikoerper, trichoplein keratin filament binding antikoerper, trichoplein, keratin filament binding antikoerper, trichoplein, keratin filament binding L homeolog antikoerper, TCHP antikoerper, tchp antikoerper, Tchp antikoerper, tchp.L antikoerper
    Hintergrund
    TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
    Alias Symbols: MGC10854, TpMs
    Protein Interaction Partner: CCDC172, MIPOL1, DYDC1, KRT40, LZTS2, NME7, NDOR1, MKRN3, TRIM27, NAB2, KRT15, CDR2, UBC, LATS2, CUL4A, CCDC85B, TEX11, VIM, KRT18, KRT16, KRT14, KRT8, KRT6A, KRT5,
    Protein Size: 498
    Molekulargewicht
    61 kDa
    Gen-ID
    84260
    NCBI Accession
    NM_032300, NP_115676
    UniProt
    Q9BT92
Sie sind hier:
Kundenservice