GFM2 Antikörper (C-Term)

Produktnummer ABIN2788489

Produktdetails anti-GFM2 Antikörper

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Bindungsspezifität: C-Term

Reaktivität: Human, Pferd, Schwein, Hund, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GFM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TVGLKHTATG DTIVSSKSSA LAAARRAERE GEKKHRQNNE AERLLLAGVE

Homologie: Cow: 79%, Dog: 93%, Horse: 86%, Human: 100%, Pig: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GFM2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human GFM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 779 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GFM2

Target: GFM2 (G Elongation Factor, Mitochondrial 2 (GFM2))

Andere Bezeichnung: GFM2 (GFM2 Produkte)

Hintergrund: Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. GFM2 is one of mitochondrial translation elongation factors. Its role in the regulation of normal mitochondrial function and in different disease states attributed to mitochondrial dysfunction is not known.
Alias Symbols: EFG2, MRRF2, MST027, RRF2, RRF2mt, hEFG2, EF-G2mt, mEF-G 2
Protein Interaction Partner: TRIM9, BANP, VPS52, TRIM27, UBC,
Protein Size: 779

Molekulargewicht: 86 kDa

Gen-ID: 84340

NCBI Accession: NM_032380, NP_115756

UniProt: Q969S9

Pathways: Ribonucleoprotein Complex Subunit Organization