ACER1 Antikörper (C-Term)

Produktnummer ABIN2788591

Produktdetails anti-ACER1 Antikörper

Target: ACER1 (Alkaline Ceramidase 1 (ACER1))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACER1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VNAYALNSIA LHILYIVCQE YRKTSNKELR HLIEVSVVLW AVALTSWISD

Homologie: Cow: 79%, Dog: 92%, Guinea Pig: 75%, Human: 100%, Pig: 85%, Rabbit: 86%, Rat: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against ACER1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ACER1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 264 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ACER1

Target: ACER1 (Alkaline Ceramidase 1 (ACER1))

Andere Bezeichnung: ACER1 (ACER1 Produkte)

Synonyme: ASAH3 antikoerper, asah3 antikoerper, zgc:110285 antikoerper, ALKCDase1 antikoerper, 2310024P18Rik antikoerper, AI662009 antikoerper, Alkcdase1 antikoerper, Asah3 antikoerper, Cer1 antikoerper, alkaline ceramidase 1 antikoerper, ACER1 antikoerper, acer1 antikoerper, Acer1 antikoerper

Hintergrund: ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.
Alias Symbols: ASAH3, MGC138327, MGC138329, ALKCDase1
Protein Size: 264

Molekulargewicht: 31 kDa

Gen-ID: 125981

NCBI Accession: NM_133492, NP_597999

UniProt: Q8TDN7