Cathepsin K Antikörper (Middle Region)
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- Target Alle Cathepsin K (CTSK) Antikörper anzeigen
- Cathepsin K (CTSK)
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Ratte, Maus, Hund, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Ziege
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cathepsin K Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- SPQNLVDCVS ENDGCGGGYM TNAFQYVQKN RGIDSEDAYP YVGQEESCMY
- Homologie
- Cow: 100%, Dog: 100%, Goat: 82%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- Produktmerkmale
- This is a rabbit polyclonal antibody against CTSK. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CTSK
- Top Product
- Discover our top product CTSK Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 329 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Cathepsin K (CTSK)
- Andere Bezeichnung
- CTSK (CTSK Produkte)
- Synonyme
- CTS02 antikoerper, CTSO antikoerper, CTSO1 antikoerper, CTSO2 antikoerper, PKND antikoerper, PYCD antikoerper, AI323530 antikoerper, MMS10-Q antikoerper, Ms10q antikoerper, catK antikoerper, CTSK antikoerper, wu:fa95f03 antikoerper, wu:fb08b05 antikoerper, zgc:110367 antikoerper, cts02 antikoerper, ctso antikoerper, ctso1 antikoerper, ctso2 antikoerper, pknd antikoerper, pycd antikoerper, OC-2 antikoerper, catk antikoerper, cathepsin K antikoerper, cathepsin K L homeolog antikoerper, Cathepsin K antikoerper, CTSK antikoerper, Ctsk antikoerper, ctsk antikoerper, ctsk.L antikoerper, catk antikoerper
- Hintergrund
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The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Alias Symbols: CTS02, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD
Protein Interaction Partner: LIG4, SERPINB13, SERPINB3, KNG1, SPARC, FGFR3,
Protein Size: 329 - Molekulargewicht
- 37 kDa
- Gen-ID
- 1513
- NCBI Accession
- NM_000396, NP_000387
- UniProt
- P43235
- Pathways
- Activation of Innate immune Response, Toll-Like Receptors Cascades
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