NQO1 Antikörper (C-Term)
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- Target Alle NQO1 Antikörper anzeigen
- NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Ratte, Hund, Rind (Kuh), Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NQO1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- WKKRLENIWD ETPLYFAPSS LFDLNFQAGF LMKKEVQDEE KNKKFGLSVG
- Homologie
- Cow: 86%, Dog: 79%, Human: 100%, Rabbit: 91%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against NQO1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human NQO1
- Top Product
- Discover our top product NQO1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 274 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
- Andere Bezeichnung
- NQO1 (NQO1 Produkte)
- Synonyme
- zgc:77191 antikoerper, wu:fb63c10 antikoerper, nqo1 antikoerper, DHQU antikoerper, DIA4 antikoerper, DTD antikoerper, NMOR1 antikoerper, NMORI antikoerper, QR1 antikoerper, Dia4 antikoerper, AV001255 antikoerper, Dtd antikoerper, Nmo-1 antikoerper, Nmo1 antikoerper, Nmor1 antikoerper, Ox-1 antikoerper, Ox1 antikoerper, Qr1 antikoerper, NADPH-d antikoerper, NAD(P)H dehydrogenase, quinone 1 antikoerper, NAD(P)H quinone dehydrogenase 1 antikoerper, NAD(P)H dehydrogenase, quinone 1 L homeolog antikoerper, nqo1 antikoerper, NQO1 antikoerper, Bpet2092 antikoerper, nqo1.L antikoerper, Nqo1 antikoerper
- Hintergrund
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This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: DHQU, DIA4, DTD, NMOR1, NMORI, QR1
Protein Interaction Partner: UBC, FOS, NEDD8, SUMO1, NFE2L2, PARP1, BAG3, ITGA4, FN1, RPS10P5, POLDIP3, YTHDF1, RPS19, LAMB1, TP53, STUB1, ING1, DNAJB1, HSPA1A, NQO1, HSPA4,
Protein Size: 274 - Molekulargewicht
- 31 kDa
- Gen-ID
- 1728
- NCBI Accession
- NM_000903, NP_000894
- UniProt
- P15559
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