Endothelin 3 Antikörper (C-Term)
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- Target Alle Endothelin 3 (EDN3) Antikörper anzeigen
- Endothelin 3 (EDN3)
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Endothelin 3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LHFCTQTLDV SSNSRTAEKT DKEEEGKVRG ANRGLCQRRL KSRTNKASRL
- Homologie
- Human: 100%, Pig: 85%
- Produktmerkmale
- This is a rabbit polyclonal antibody against EDN3. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human EDN3
- Top Product
- Discover our top product EDN3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 219 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Endothelin 3 (EDN3)
- Andere Bezeichnung
- EDN3 (EDN3 Produkte)
- Synonyme
- et-3 antikoerper, EDN3 antikoerper, ET-3 antikoerper, ET3 antikoerper, HSCR4 antikoerper, PPET3 antikoerper, WS4B antikoerper, 114CH19 antikoerper, ls antikoerper, tmgc48 antikoerper, Et3 antikoerper, RGD1564825 antikoerper, preproET-3 antikoerper, endothelin-3 L homeolog antikoerper, endothelin 3 antikoerper, edn3.L antikoerper, EDN3 antikoerper, Edn3 antikoerper
- Hintergrund
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The protein encoded by this gene is a member of the endothelin family. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. The active form of this protein is a 21 amino acid peptide processed from the precursor protein. The active peptide is a ligand for endothelin receptor type B (EDNRB). The interaction of this endothelin with EDNRB is essential for development of neural crest-derived cell lineages, such as melanocytes and enteric neurons. Mutations in this gene and EDNRB have been associated with Hirschsprung disease (HSCR) and Waardenburg syndrome (WS), which are congenital disorders involving neural crest-derived cells. Four alternatively spliced transcript variants encoding three distinct isoforms have been observed.
Alias Symbols: ET3, MGC15067, MGC61498, ET-3, WS4B, HSCR4, PPET3
Protein Interaction Partner: EDNRB, EDNRA, CMA1, CTSE, KEL,
Protein Size: 219 - Molekulargewicht
- 24 kDa
- Gen-ID
- 1908
- NCBI Accession
- NM_207032, NP_996915
- UniProt
- P14138
- Pathways
- Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones
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