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KPNB1 Antikörper (N-Term)

KPNB1 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2788708
  • Target Alle KPNB1 Antikörper anzeigen
    KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
    Bindungsspezifität
    • 15
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 45
    • 17
    • 16
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen
    Wirt
    • 42
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 43
    • 3
    Polyklonal
    Konjugat
    • 22
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KPNB1 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 13
    • 13
    • 11
    • 10
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    EHMKESTLEA IGYICQDIDP EQLQDKSNEI LTAIIQGMRK EEPSNNVKLA
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against KPNB1. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Top Product
    Discover our top product KPNB1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 876 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
    Andere Bezeichnung
    KPNB1 (KPNB1 Produkte)
    Synonyme
    Afu1g15720 antikoerper, AO090005001133 antikoerper, imb1 antikoerper, impnb antikoerper, ipo1 antikoerper, ipob antikoerper, ntf97 antikoerper, IMB1 antikoerper, IPO1 antikoerper, IPOB antikoerper, Impnb antikoerper, NTF97 antikoerper, AA409963 antikoerper, importin beta-1 subunit antikoerper, Importin beta-1 subunit antikoerper, karyopherin (importin) beta 1 L homeolog antikoerper, importin beta 1 antikoerper, karyopherin subunit beta 1 antikoerper, karyopherin (importin) beta 1 antikoerper, AFUA_1G15720 antikoerper, AOR_1_1974174 antikoerper, Bm1_57540 antikoerper, PMAA_065830 antikoerper, AFLA_083750 antikoerper, TSTA_085870 antikoerper, BDBG_07509 antikoerper, MCYG_00039 antikoerper, kpnb1.L antikoerper, LOC100533387 antikoerper, KPNB1 antikoerper, Kpnb1 antikoerper
    Hintergrund
    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
    Alias Symbols: IMB1, IPO1, IPOB, Impnb, MGC2155, MGC2156, MGC2157, NTF97
    Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, SUMO3, STAU1, MDM2, EED, rev, CUL2, NLK, FBXO6, DYRK1B, CLK3, CDK11A, EGFR, SAMHD1, UBD, PTMA, ADRB2, RASSF5, AICDA, UBL4A, VCAM1, TAF10, NOS2, SMAD2, TAF8, TAF3, ITGA4, FN1, ERBB2, CFTR, YWHAE, SMURF1, ECT2, BARD1, MDC1, TP53BP1,
    Protein Size: 876
    Molekulargewicht
    96 kDa
    Gen-ID
    3837
    NCBI Accession
    NM_002265, NP_002256
    UniProt
    Q14974
    Pathways
    Protein targeting to Nucleus
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