PVRL1 Antikörper (N-Term)
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- Target Alle PVRL1 Antikörper anzeigen
- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PVRL1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- QLNLTVMAKP TNWIEGTQAV LRAKKGQDDK VLVATCTSAN GKPPSVVSWE
- Homologie
- Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PVRL1. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product PVRL1 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 517 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))
- Andere Bezeichnung
- PVRL1 (PVRL1 Produkte)
- Synonyme
- CD111 antikoerper, CLPED1 antikoerper, ED4 antikoerper, HIgR antikoerper, HVEC antikoerper, OFC7 antikoerper, PRR antikoerper, PRR1 antikoerper, PVRR antikoerper, PVRR1 antikoerper, SK-12 antikoerper, nectin-1 antikoerper, prr1 antikoerper, PVRL1 antikoerper, pvrl1 antikoerper, AI835281 antikoerper, AW549174 antikoerper, Cd111 antikoerper, HveC antikoerper, cd111 antikoerper, cd112 antikoerper, clped1 antikoerper, ed4 antikoerper, higr antikoerper, hveb antikoerper, hvec antikoerper, nectin-2 antikoerper, ofc7 antikoerper, prr antikoerper, prr2 antikoerper, pvrl2 antikoerper, pvrl2.L antikoerper, pvrr antikoerper, pvrr1 antikoerper, pvrr2 antikoerper, sk-12 antikoerper, nectin cell adhesion molecule 1 antikoerper, nectin-1 antikoerper, Poliovirus receptor-related protein 1 antikoerper, poliovirus receptor-related 1 (herpesvirus entry mediator C) antikoerper, nectin cell adhesion molecule 2 L homeolog antikoerper, NECTIN1 antikoerper, LOC100145553 antikoerper, pvrl1 antikoerper, nectin1 antikoerper, Nectin1 antikoerper, PVRL1 antikoerper, nectin2.L antikoerper
- Hintergrund
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This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.
Alias Symbols: CD111, CLPED1, ED4, HIgR, HVEC, MGC142031, MGC16207, OFC7, PRR, PRR1, PVRR, PVRR1, SK-12, nectin-1
Protein Interaction Partner: UBC, PVRL4, PVRL3, PVRL1, PARD3, PRNP, PVR, MLLT4,
Protein Size: 517 - Molekulargewicht
- 57 kDa
- Gen-ID
- 5818
- NCBI Accession
- NM_002855, NP_002846
- UniProt
- Q15223
- Pathways
- Cell-Cell Junction Organization
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