GBA Antikörper (C-Term)

Produktnummer ABIN2788767

Produktdetails anti-GBA Antikörper

Target: GBA (Glucosidase, Beta, Acid (GBA))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Schwein, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GBA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EGSQRVGLVA SQKNDLDAVA LMHPDGSAVV VVLNRSSKDV PLTIKDPAVG

Homologie: Cow: 92%, Dog: 86%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 83%, Pig: 100%, Rabbit: 86%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against GBA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 536 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GBA

Target: GBA (Glucosidase, Beta, Acid (GBA))

Andere Bezeichnung: GBA (GBA Produkte)

Synonyme: GBA1 antikoerper, GCB antikoerper, GLUC antikoerper, BETA-GLUCOSIDASE antikoerper, T12J13.8 antikoerper, T12J13_8 antikoerper, beta glucosidase 25 antikoerper, PSPTO3318 antikoerper, PSPTO4290 antikoerper, GC antikoerper, GCase antikoerper, betaGC antikoerper, glucosylceramidase beta antikoerper, beta glucosidase 25 antikoerper, beta-glucosidase antikoerper, Beta-glucosidase antikoerper, glucosidase, beta, acid antikoerper, glucosylceramidase antikoerper, bglX-2 antikoerper, GBA antikoerper, BGLU25 antikoerper, PSPTO_3318 antikoerper, bglX antikoerper, bglA4 antikoerper, Gba antikoerper, LOC100399524 antikoerper, bglA.2 antikoerper, bglX-2 antikoerper

Hintergrund: This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
Alias Symbols: GBA1, GCB, GLUC
Protein Interaction Partner: NUDCD1, UBC, ITCH, ATP6V1B1, SNCA, FBXO6, TCP1, CBL, NEDD4, PARK2, HSP90AA1, HSPA4, PSAP,
Protein Size: 536

Molekulargewicht: 59 kDa

Gen-ID: 2629

NCBI Accession: NM_000157, NP_000148

UniProt: P04062

Pathways: Cellular Glucan Metabolic Process