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GBA Antikörper (C-Term)

GBA Reaktivität: Human, Maus, Ratte, Schwein, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2788767
  • Target Alle GBA Antikörper anzeigen
    GBA (Glucosidase, Beta, Acid (GBA))
    Bindungsspezifität
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    Human, Maus, Ratte, Schwein, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen
    Wirt
    • 62
    • 10
    Kaninchen
    Klonalität
    • 56
    • 16
    Polyklonal
    Konjugat
    • 31
    • 15
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser GBA Antikörper ist unkonjugiert
    Applikation
    • 51
    • 25
    • 25
    • 8
    • 8
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    EGSQRVGLVA SQKNDLDAVA LMHPDGSAVV VVLNRSSKDV PLTIKDPAVG
    Homologie
    Cow: 92%, Dog: 86%, Guinea Pig: 86%, Horse: 85%, Human: 100%, Mouse: 83%, Pig: 100%, Rabbit: 86%, Rat: 92%
    Produktmerkmale
    This is a rabbit polyclonal antibody against GBA. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Top Product
    Discover our top product GBA Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 536 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    GBA (Glucosidase, Beta, Acid (GBA))
    Andere Bezeichnung
    GBA (GBA Produkte)
    Synonyme
    GBA1 antikoerper, GCB antikoerper, GLUC antikoerper, BETA-GLUCOSIDASE antikoerper, T12J13.8 antikoerper, T12J13_8 antikoerper, beta glucosidase 25 antikoerper, PSPTO3318 antikoerper, PSPTO4290 antikoerper, GC antikoerper, GCase antikoerper, betaGC antikoerper, glucosylceramidase beta antikoerper, beta glucosidase 25 antikoerper, beta-glucosidase antikoerper, Beta-glucosidase antikoerper, glucosidase, beta, acid antikoerper, glucosylceramidase antikoerper, bglX-2 antikoerper, GBA antikoerper, BGLU25 antikoerper, PSPTO_3318 antikoerper, bglX antikoerper, bglA4 antikoerper, Gba antikoerper, LOC100399524 antikoerper, bglA.2 antikoerper, bglX-2 antikoerper
    Hintergrund
    This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
    Alias Symbols: GBA1, GCB, GLUC
    Protein Interaction Partner: NUDCD1, UBC, ITCH, ATP6V1B1, SNCA, FBXO6, TCP1, CBL, NEDD4, PARK2, HSP90AA1, HSPA4, PSAP,
    Protein Size: 536
    Molekulargewicht
    59 kDa
    Gen-ID
    2629
    NCBI Accession
    NM_000157, NP_000148
    UniProt
    P04062
    Pathways
    Cellular Glucan Metabolic Process
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