EIF6 Antikörper (C-Term)

Produktnummer ABIN2788786

Produktdetails anti-EIF6 Antikörper

Target: EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Schaf, Hund, Meerschweinchen, Pferd, Saccharomyces cerevisiae, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: QVLVGSYCVF SNQGGLVHPK TSIEDQDELS SLLQVPLVAG TVNRGSEVIA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 93%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF6. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 245 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF6

Target: EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Andere Bezeichnung: EIF6 (EIF6 Produkte)

Hintergrund: Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits.
Alias Symbols: 2, CAB, EIF3A, ITGB4BP, b, b(2)gcn, gcn, p27BBP, eIF-6, p27(BBP)
Protein Interaction Partner: ZNF622, BCCIP, PPAN, NMD3, GLTSCR2, GTPBP4, POP1, TOP2B, TOP2A, RNF2, CNBP, RARS, PPP5C, PEPD, PAFAH1B2, HSPA9, HSPA1A, HPRT1, EIF4E, DFFA, CFL1, CAPN1, ASNA1, GINS3, BZW2, ABHD14A, TNFAIP8, XRN2, HDAC9, ZBTB26, VCAM1, UBC, ECT2, HNRNPU, FBL, DHX9, APP, R
Protein Size: 245

Molekulargewicht: 27 kDa

Gen-ID: 3692

NCBI Accession: NM_002212, NP_002203

UniProt: P56537

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly