GALR2 Antikörper (C-Term)
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- Target Alle GALR2 Antikörper anzeigen
- GALR2 (Galanin Receptor 2 (GALR2))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GALR2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- RGTHSGSVLE RESSDLLHMS EAAGALRPCP GASQPCILEP CPGPSWQGPK
- Homologie
- Horse: 93%, Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against GALR2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product GALR2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 387 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GALR2 (Galanin Receptor 2 (GALR2))
- Andere Bezeichnung
- GALR2 (GALR2 Produkte)
- Synonyme
- GALNR2 antikoerper, mGalR antikoerper, GALR2 antikoerper, GAL2-R antikoerper, GALR-2 antikoerper, galanin receptor 2 antikoerper, transcription regulator. LacI family, raffinose related antikoerper, DNA-binding transcriptional regulator GalR antikoerper, galactose operon repressor antikoerper, galanin receptor type 2 antikoerper, GALR2 antikoerper, Galr2 antikoerper, LOC100037698 antikoerper, rafR antikoerper, galR2 antikoerper, LOC103690156 antikoerper
- Hintergrund
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Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.
Alias Symbols: GALNR2, MGC125983, MGC125984
Protein Interaction Partner: GNAQ, GAL,
Protein Size: 387 - Molekulargewicht
- 43 kDa
- Gen-ID
- 8811
- NCBI Accession
- NM_003857, NP_003848
- UniProt
- O43603
- Pathways
- cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour
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