AKR1C3 Antikörper (N-Term)
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- Target Alle AKR1C3 Antikörper anzeigen
- AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Kaninchen, Ratte, Maus, Rind (Kuh), Schwein, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser AKR1C3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- PALENSLKKA QLDYVDLYLI HSPMSLKPGE ELSPTDENGK VIFDIVDLCT
- Homologie
- Cow: 85%, Guinea Pig: 85%, Human: 100%, Mouse: 77%, Pig: 92%, Rabbit: 86%, Rat: 85%
- Produktmerkmale
- This is a rabbit polyclonal antibody against AKR1C3. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product AKR1C3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 323 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
- Andere Bezeichnung
- AKR1C3 (AKR1C3 Produkte)
- Synonyme
- AKR1C3 antikoerper, PGFS antikoerper, MGC134333 antikoerper, DD3 antikoerper, DDX antikoerper, HA1753 antikoerper, HAKRB antikoerper, HAKRe antikoerper, HSD17B5 antikoerper, hluPGFS antikoerper, Akr1c18 antikoerper, aldo-keto reductase family 1, member C3 L homeolog antikoerper, aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) antikoerper, aldo-keto reductase family 1 member C2 antikoerper, aldo-keto reductase family 1 member C3 antikoerper, aldo-keto reductase family 1, member C3 antikoerper, akr1c3.L antikoerper, AKR1C3 antikoerper, LOC722496 antikoerper, Akr1c3 antikoerper
- Hintergrund
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, KIAA0119, hluPGFS
Protein Interaction Partner: UBC, LRIF1, ZHX1, UBE2W, ACIN1, MAGEA11,
Protein Size: 323 - Molekulargewicht
- 36 kDa
- Gen-ID
- 8644
- NCBI Accession
- NM_003739, NP_003730
- UniProt
- P42330
- Pathways
- Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Protein targeting to Nucleus
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