EIF5B Antikörper (Middle Region)

Produktnummer ABIN2788862

Produktdetails anti-EIF5B Antikörper

Target: EIF5B (Eukaryotic Translation Initiation Factor 5B (EIF5B))

Bindungsspezifität: Middle Region

Reaktivität: Human, Pferd, Hund, Schwein, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF5B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SEGSEGDEED EKVSDEKDSG KTLDKKPSKE MSSDSEYDSD DDRTKEERAY

Homologie: Cow: 86%, Dog: 86%, Horse: 86%, Human: 100%, Pig: 93%, Rabbit: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF5B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1220 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF5B

Target: EIF5B (Eukaryotic Translation Initiation Factor 5B (EIF5B))

Andere Bezeichnung: EIF5B (EIF5B Produkte)

Hintergrund: Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.
Alias Symbols: DKFZp434I036, FLJ10524, IF2, KIAA0741
Protein Interaction Partner: TP53, TFCP2, UBC, LGR4, YBX3, ETS1, MMS19, FN1, CSNK2A1, PAXIP1, ECT2, BRCA1, EIF3C, CAND1, YWHAZ, SIRT7, HDGF, Mapk13, POU5F1, ZBTB3, PRKAA1, EIF1AX, CBL, gag,
Protein Size: 1220

Molekulargewicht: 139 kDa

Gen-ID: 9669

NCBI Accession: NM_015904, NP_056988

UniProt: O60841