RPL7A Antikörper (C-Term)

Produktnummer ABIN2788883

Produktdetails anti-RPL7A Antikörper

Target: RPL7A (Ribosomal Protein L7a (RPL7A))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPL7A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KLVEAIRTNY NDRYDEIRRH WGGNVLGPKS VARIAKLEKA KAKELATKLG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RPL7A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 266 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RPL7A

Target: RPL7A (Ribosomal Protein L7a (RPL7A))

Andere Bezeichnung: RPL7A (RPL7A Produkte)

Synonyme: CG3314 antikoerper, Dmel\\CG3314 antikoerper, L7A antikoerper, L7a antikoerper, Rp L7A antikoerper, Surf-3/rpL7a antikoerper, Surf3/rpL7a antikoerper, rpl7a antikoerper, surf3 antikoerper, SURF3 antikoerper, TRUP antikoerper, Surf3 antikoerper, wu:fa95b03 antikoerper, zgc:73183 antikoerper, zgc:86667 antikoerper, Ribosomal protein L7A antikoerper, 60S ribosomal protein L7a antikoerper, ribosomal protein L7a antikoerper, ribosomal protein L7A antikoerper, RpL7A antikoerper, LOC100525692 antikoerper, rpl7a antikoerper, RPL7A antikoerper, Rpl7a antikoerper

Hintergrund: Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L7AE family of ribosomal proteins. It can interact with a subclass of nuclear hormone receptors, including thyroid hormone receptor, and inhibit their ability to transactivate by preventing their binding to their DNA response elements. This gene is included in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity. It is co-transcribed with the U24, U36a, U36b, and U36c small nucleolar RNA genes, which are located in its second, fifth, fourth, and sixth introns, respectively. This gene rearranges with the trk proto-oncogene to form the chimeric oncogene trk-2h, which encodes an oncoprotein consisting of the N terminus of ribosomal protein L7a fused to the receptor tyrosine kinase domain of trk. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Alias Symbols: SURF3, TRUP, L7A
Protein Interaction Partner: HUWE1, UBC, TP53, SUMO2, CEP250, STAU1, MDM2, EED, RNF2, EEF1E1, AIMP1, DARS, RPL36, RPLP0, RPL26, RPL23A, RPL21, RPL15, RPL13, QARS, EIF2S1, TRAP1, PARK2, FBXO6, TARDBP, IGSF8, ICAM1, PAN2, SOCS3, UBL4A, VCAM1, ITGA4, FN1, CTBP2, MAGOH, EIF4A3, UPF1, ESR
Protein Size: 266

Molekulargewicht: 29 kDa

Gen-ID: 6130

NCBI Accession: NM_000972, NP_000963

UniProt: P62424