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CTPS2 Antikörper (N-Term)

CTPS2 Reaktivität: Human, Maus, Ratte, Pferd, Hund, Schwein, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2789147
  • Target Alle CTPS2 Antikörper anzeigen
    CTPS2 (CTP Synthase II (CTPS2))
    Bindungsspezifität
    • 9
    • 8
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    N-Term
    Reaktivität
    • 43
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Pferd, Hund, Schwein, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen
    Wirt
    • 43
    Kaninchen
    Klonalität
    • 43
    Polyklonal
    Konjugat
    • 19
    • 6
    • 5
    • 5
    • 4
    • 4
    Dieser CTPS2 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 29
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    AKRENFCNIH VSLVPQLSAT GEQKTKPTQN SVRALRGLGL SPDLIVCRSS
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against CTPS2. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Top Product
    Discover our top product CTPS2 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 586 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    CTPS2 (CTP Synthase II (CTPS2))
    Andere Bezeichnung
    CTPS2 (CTPS2 Produkte)
    Synonyme
    A830031M15Rik antikoerper, AI326475 antikoerper, Ctpsh antikoerper, CTP synthase 2 L homeolog antikoerper, CTP synthase 2 antikoerper, cytidine 5'-triphosphate synthase 2 antikoerper, ctps2.L antikoerper, CTPS2 antikoerper, ctps2 antikoerper, Ctps2 antikoerper
    Hintergrund
    The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.
    Alias Symbols: DKFZp686C17207, FLJ43358, MGC32997
    Protein Interaction Partner: CTPS2, SPG21, RNF2, LRSAM1, EHD4, EHD1, PLIN3, MTMR2, WARS, PRKDC, NUCB1, METTL1, KTN1, HSF1, GTF2I, DHPS, RPL37A, RPL23A, FGFR1, CTBP2, UBC, SUMO2, OTUD5,
    Protein Size: 586
    Molekulargewicht
    64 kDa
    Gen-ID
    56474
    NCBI Accession
    NM_175859, NP_787055
    UniProt
    Q9NRF8
    Pathways
    Ribonucleoside Biosynthetic Process
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