HLA-E Antikörper (C-Term)
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- Target Alle HLA-E Antikörper anzeigen
- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HLA-E Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- IPIVGIIAGL VLLGSVVSGA VVAAVIWRKK SSGGKGGSYS KAEWSDSAQG
- Homologie
- Human: 100%, Mouse: 100%, Pig: 92%
- Produktmerkmale
- This is a rabbit polyclonal antibody against HLA-E. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product HLA-E Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 358 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HLA-E (HLA Class I Histocompatibility Antigen, alpha Chain E (HLA-E))
- Andere Bezeichnung
- HLA-E (HLA-E Produkte)
- Synonyme
- EA1.2 antikoerper, EA2.1 antikoerper, HLA-6.2 antikoerper, MHC antikoerper, QA1 antikoerper, major histocompatibility complex, class I, E antikoerper, HLA-E antikoerper, PATR-E antikoerper
- Hintergrund
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HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.
Alias Symbols: DKFZp686P19218, EA1.2, EA2.1, HLA-6.2, MHC, QA1
Protein Interaction Partner: UBC, CALR, TAP2, UBD, PPP1R16A, KLRD1, KLRC2, CD8A, KLRC1, HLA-E, B2M,
Protein Size: 358 - Molekulargewicht
- 38 kDa
- Gen-ID
- 3133
- NCBI Accession
- NM_005516, NP_005507
- UniProt
- P13747
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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