PLAUR Antikörper (N-Term)
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- Target Alle PLAUR Antikörper anzeigen
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PLAUR Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- ELELVEKSCT HSEKTNRTLS YRTGLKITSL TEVVCGLDLC NQGNSGRAVT
- Homologie
- Human: 100%, Mouse: 82%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PLAUR. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of PLAUR
- Top Product
- Discover our top product PLAUR Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 335 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
- Andere Bezeichnung
- PLAUR (PLAUR Produkte)
- Synonyme
- Cd87 antikoerper, u-PAR antikoerper, uPAR antikoerper, CD87 antikoerper, U-PAR antikoerper, UPAR antikoerper, URKR antikoerper, Par antikoerper, Plaur3 antikoerper, uPAR-2 antikoerper, uPAR-3 antikoerper, PLAUR antikoerper, plasminogen activator, urokinase receptor antikoerper, Plaur antikoerper, PLAUR antikoerper
- Hintergrund
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This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
Alias Symbols: CD87, UPAR, URKR
Protein Interaction Partner: TEX101, PLAU, LYN, ELAVL1, VMA21, TXNDC17, SCAF4, SDHAF2, UBQLN2, WDHD1, SELENBP1, TBCA, PSAP, CTSA, OXCT1, NOTCH2, HDLBP, CTTN, LRP1B, SURF2, SRPX2, MMP12, IL6ST, FAP, KNG1, VTN, TYK2, PFN2, JAK1, HCK, FYN, ITGB1, EEF1A1, ITGAM, LRP1, IGF2R, ITGB2, PDGFR
Protein Size: 335 - Molekulargewicht
- 37 kDa
- Gen-ID
- 5329
- NCBI Accession
- NM_002659, NP_002650
- UniProt
- Q9GK80
- Pathways
- Inositol Metabolic Process
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