PDE5A Antikörper (C-Term)

Produktnummer ABIN2789423

Produktdetails anti-PDE5A Antikörper

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE5A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: TACDLSAITK PWPIQQRIAE LVATEFFDQG DRERKELNIE PTDLMNREKK

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 82%

Produktmerkmale: This is a rabbit polyclonal antibody against PDE5A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 823 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PDE5A Antikörper (ABIN2789423)

Ioki, Wu, Takayama, Motohashi, Wakai, Funahashi: "A phosphodiesterase type-5 inhibitor, sildenafil, induces sperm capacitation and penetration into porcine oocytes in a chemically defined medium." in: Theriogenology, Vol. 85, Issue 3, pp. 428-33, (2016) (PubMed).

Details zu PDE5A

Target: PDE5A (phosphodiesterase 5A, cGMP-Specific (PDE5A))

Andere Bezeichnung: PDE5A (PDE5A Produkte)

Synonyme: CGB-PDE antikoerper, CN5A antikoerper, PDE5 antikoerper, PDE5A2 antikoerper, Cgbpde antikoerper, Cn5n antikoerper, Pde5 antikoerper, Pde5a1 antikoerper, PDE5A antikoerper, pde5a antikoerper, cgb-pde antikoerper, cn5a antikoerper, pde5 antikoerper, pde5a1 antikoerper, phosphodiesterase 5A antikoerper, phosphodiesterase 5A, cGMP-specific antikoerper, phosphodiesterase 5A S homeolog antikoerper, phosphodiesterase 5A, cGMP-specific, b antikoerper, PDE5A antikoerper, Pde5a antikoerper, pde5a.S antikoerper, pde5ab antikoerper, pde5a antikoerper

Hintergrund: This gene encodes a cGMP-binding, cGMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5'-GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.
Alias Symbols: CGB-PDE, CN5A, PDE5, PDE5A1
Protein Interaction Partner: UBC, PRKG1, CASP3,
Protein Size: 823

Molekulargewicht: 93 kDa

Gen-ID: 8654

NCBI Accession: NM_033437, NP_246273

UniProt: O76074

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling