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VKORC1 Antikörper (N-Term)

VKORC1 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2789450
  • Target Alle VKORC1 Antikörper anzeigen
    VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
    Bindungsspezifität
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd
    Wirt
    • 22
    Kaninchen
    Klonalität
    • 22
    Polyklonal
    Konjugat
    • 7
    • 4
    • 4
    • 3
    • 2
    • 2
    Dieser VKORC1 Antikörper ist unkonjugiert
    Applikation
    • 18
    • 18
    • 16
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Sequenz
    LHVKAARARD RDYRALCDVG TAISCSRVFS SRLPADTLGL CPDAAELPGV
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%
    Produktmerkmale
    This is a rabbit polyclonal antibody against VKORC1. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N-terminal region of VKORC1
    Top Product
    Discover our top product VKORC1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 92 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    VKORC1 (Vitamin K Epoxide Reductase Complex, Subunit 1 (VKORC1))
    Andere Bezeichnung
    VKORC1 (VKORC1 Produkte)
    Synonyme
    MGC89620 antikoerper, BP1071 antikoerper, CG33544 antikoerper, Dmel\\CG33544 antikoerper, HDC06808 antikoerper, VKORC1 antikoerper, EDTP308 antikoerper, IMAGE3455200 antikoerper, MST134 antikoerper, MST576 antikoerper, VKCFD2 antikoerper, VKOR antikoerper, D7Wsu86e antikoerper, vitamin K epoxide reductase complex, subunit 1 antikoerper, vitamin K epoxide reductase complex subunit 1 antikoerper, Vitamin-K epoxide reductase antikoerper, VKORC1 antikoerper, vkorc1 antikoerper, Vkor antikoerper, Vkorc1 antikoerper
    Hintergrund
    Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. Two pseudogenes have been identified on chromosome 1 and the X chromosome. Two alternatively spliced transcripts encoding different isoforms have been described.
    Alias Symbols: EDTP308, FLJ00289, IMAGE3455200, MGC2694, MST134, MST576, VKCFD2, VKOR
    Protein Interaction Partner: UBC, ILK, ZMYM6NB, TMEM242, SNORA12, TMEM256, ZCCHC24, METTL7B, SPTSSA, VKORC1L1, CCDC167, CCDC12, TMEM45B, KCNK17, JAGN1, SERP1, PPA2, TRAM1, TREX1, YIF1A, EBP, ARL6IP5, PROCR, IFITM3, ATP6AP2, BCAP31, PDIA6, HDAC6, HOMER2, VAPB, CLDN10, DPM2, REEP5, TF,
    Protein Size: 92
    Molekulargewicht
    10 kDa
    Gen-ID
    79001
    NCBI Accession
    NM_206824, NP_996560
    UniProt
    Q9BQB6
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