KIR2DS2 Antikörper (N-Term)
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- Target Alle KIR2DS2 Antikörper anzeigen
- KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser KIR2DS2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- ETVILQCWSD VRFEHFLLHR EGKYKDTLHL IGEHHDGVSK ANFSIGPMMQ
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against KIR2DS2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product KIR2DS2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 304 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- KIR2DS2 (Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
- Andere Bezeichnung
- KIR2DS2 (KIR2DS2 Produkte)
- Synonyme
- 183ActI antikoerper, CD158J antikoerper, CD158b antikoerper, NKAT5 antikoerper, cl-49 antikoerper, killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 antikoerper, KIR2DS2 antikoerper
- Hintergrund
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Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
Alias Symbols: CU464060.1, 183ActI, CD158J, CD158b, NKAT5, cl-49
Protein Interaction Partner: TYROBP, HLA-C, KIR2DS2,
Protein Size: 304 - Molekulargewicht
- 32 kDa
- Gen-ID
- 100132285
- NCBI Accession
- NM_012312, NP_036444
- UniProt
- D0UWM7
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