ARTN Antikörper (Middle Region)
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- Target Alle ARTN Antikörper anzeigen
- ARTN (Artemin (ARTN))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ARTN Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- RTARWCSGRA RRPPPQPSRP APPPPAPPSA LPRGGRAARA GGPGSRARAA
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against ARTN. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product ARTN Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 228 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- ARTN (Artemin (ARTN))
- Andere Bezeichnung
- ARTN (ARTN Produkte)
- Synonyme
- ARTN antikoerper, ENOVIN antikoerper, EVN antikoerper, NBN antikoerper, neublastin antikoerper, artemin antikoerper, ARTN antikoerper, Artn antikoerper
- Hintergrund
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The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecules. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in culture to support the survival of a number of peripheral neuron populations and at least one population of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ENOVIN, EVN, NBN
Protein Interaction Partner: GFRA3, ARTN,
Protein Size: 228 - Molekulargewicht
- 19 kDa
- Gen-ID
- 9048
- NCBI Accession
- NM_057090, NP_476431
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