FGF20 Antikörper (C-Term)

Produktnummer ABIN2789708

Produktdetails anti-FGF20 Antikörper

Target: FGF20 (Fibroblast Growth Factor 20 (FGF20))

Bindungsspezifität: C-Term

Reaktivität: Maus, Ratte, Human, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio), Schaf, Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF20 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IFREQFEENW YNTYSSNIYK HGDTGRRYFV ALNKDGTPRD GARSKRHQKF

Homologie: Cow: 100%, Dog: 100%, Goat: 77%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 77%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FGF20. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 211 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FGF20

Target: FGF20 (Fibroblast Growth Factor 20 (FGF20))

Andere Bezeichnung: FGF20 (FGF20 Produkte)

Hintergrund: The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility.
Alias Symbols: FGF-20
Protein Interaction Partner: CTNNB1,
Protein Size: 211

Molekulargewicht: 23 kDa

Gen-ID: 26281

NCBI Accession: NM_019851, NP_062825

UniProt: Q9NP95

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung