PDE11A Antikörper (N-Term)
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- Target Alle PDE11A Antikörper anzeigen
- PDE11A (phosphodiesterase 11A (PDE11A))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio), Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PDE11A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- RRASQKELRK SFARSKAIHV NRTYDEQVTS RAQEPLSSVR RRALLRKASS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PDE11A. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product PDE11A Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 933 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PDE11A (phosphodiesterase 11A (PDE11A))
- Andere Bezeichnung
- PDE11A (PDE11A Produkte)
- Synonyme
- PPNAD2 antikoerper, 6330414F14Rik antikoerper, A630086N24Rik antikoerper, Gm350 antikoerper, PDE11A1 antikoerper, si:ch211-222f23.5 antikoerper, PDE11A antikoerper, ppnad2 antikoerper, Pde11a antikoerper, phosphodiesterase 11A antikoerper, phosphodiesterase 11a antikoerper, dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A antikoerper, PDE11A antikoerper, Pde11a antikoerper, pde11a antikoerper, LOC100470038 antikoerper
- Hintergrund
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The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FLJ23693, MGC133355, MGC133356, PPNAD2
Protein Size: 933 - Molekulargewicht
- 105 kDa
- Gen-ID
- 50940
- NCBI Accession
- NM_016953, NP_058649
- UniProt
- Q9HCR9
- Pathways
- cAMP Metabolic Process
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