IL-19 Antikörper (Middle Region)

Produktnummer ABIN2789718

Produktdetails anti-IL-19 Antikörper

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Hund, Rind (Kuh), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ILSTLETLQI IKPLDVCCVT KNLLAFYVDR VFKDHQEPNP KILRKISSIA

Homologie: Cow: 79%, Dog: 86%, Human: 100%, Rabbit: 79%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against IL19. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 215 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IL-19

Target: IL-19 (IL19) (Interleukin 19 (IL19))

Andere Bezeichnung: IL19 (IL19 Produkte)

Synonyme: IL-10C antikoerper, MDA1 antikoerper, NG.1 antikoerper, ZMDA1 antikoerper, IL19 antikoerper, interleukin 19 antikoerper, IL19 antikoerper, Il19 antikoerper

Hintergrund: The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
Alias Symbols: IL-10C, MDA1, NG.1, ZMDA1
Protein Interaction Partner: IL20RA,
Protein Size: 215

Molekulargewicht: 18 kDa

Gen-ID: 29949

NCBI Accession: NM_153758, NP_715639

UniProt: Q5VUT3