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Melatonin Receptor 1B Antikörper (N-Term)

MTNR1B Reaktivität: Human, Schwein, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2789720
  • Target Alle Melatonin Receptor 1B (MTNR1B) Antikörper anzeigen
    Melatonin Receptor 1B (MTNR1B)
    Bindungsspezifität
    • 15
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 41
    • 19
    • 17
    • 15
    • 1
    Human, Schwein, Kaninchen
    Wirt
    • 44
    • 1
    Kaninchen
    Klonalität
    • 45
    Polyklonal
    Konjugat
    • 19
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Melatonin Receptor 1B Antikörper ist unkonjugiert
    Applikation
    • 27
    • 18
    • 13
    • 13
    • 12
    • 6
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    SFANCCEAGG WAVRPGWSGA GSARPSRTPR PPWVAPALSA VLIVTTAVDV
    Homologie
    Human: 100%, Pig: 79%, Rabbit: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against MTNR1B. It was validated on Western Blot.
    Aufreinigung
    Affinity Purified
    Top Product
    Discover our top product MTNR1B Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 362 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Santoro, Mori, Marani, Grasso, Cambria, Blandino, Muti, Strano: "Blockage of melatonin receptors impairs p53-mediated prevention of DNA damage accumulation." in: Carcinogenesis, Vol. 34, Issue 5, pp. 1051-61, (2013) (PubMed).

  • Target
    Melatonin Receptor 1B (MTNR1B)
    Andere Bezeichnung
    MTNR1B (MTNR1B Produkte)
    Synonyme
    FGQTL2 antikoerper, MEL-1B-R antikoerper, MT2 antikoerper, Mel1b-r antikoerper, Mel-1B-R antikoerper, MTNR1B antikoerper, mtnr1br antikoerper, MEL1B antikoerper, Mel1b antikoerper, Mt2 antikoerper, mel1b antikoerper, mtnr1b antikoerper, melatonin receptor 1B antikoerper, melatonin receptor type 1C S homeolog antikoerper, melatonin receptor type 1Ba antikoerper, MTNR1B antikoerper, Mtnr1b antikoerper, mtnr1c.S antikoerper, mtnr1bb antikoerper, mtnr1ba antikoerper
    Hintergrund
    This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin.
    Alias Symbols: FGQTL2, MEL-1B-R, MT2
    Protein Interaction Partner: GNAI1, GPR50, ITM2C, HNRNPA0, GNB4, PPM1G, PI4KA, PDIA6, VPS35, IRS4, COPA, CTNND1, MTNR1B, MTNR1A, FLNA, YWHAQ, GNB1, GNAI3, GNAI2, HSPA5, CANX,
    Protein Size: 362
    Molekulargewicht
    40 kDa
    Gen-ID
    4544
    NCBI Accession
    NM_005959, NP_005950
    UniProt
    P49286
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