SYNGAP1 Antikörper (C-Term)

Produktnummer ABIN2789829

Produktdetails anti-SYNGAP1 Antikörper

Target: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYNGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EYKLKEYSKS MDESRLDRVK EYEEEIHSLK ERLHMSNRKL EEYERRLLSQ

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SYNGAP1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1343 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SYNGAP1

Target: SYNGAP1 (Synaptic Ras GTPase Activating Protein 1 (SYNGAP1))

Andere Bezeichnung: SYNGAP1 (SYNGAP1 Produkte)

Synonyme: SYNGAP1 antikoerper, Syngap antikoerper, MRD5 antikoerper, RASA1 antikoerper, RASA5 antikoerper, SYNGAP antikoerper, Gm1963 antikoerper, synaptic Ras GTPase activating protein 1 antikoerper, zinc finger and BTB domain containing 9 antikoerper, synaptic Ras GTPase activating protein 1 homolog (rat) antikoerper, SYNGAP1 antikoerper, ZBTB9 antikoerper, syngap1 antikoerper, Syngap1 antikoerper

Hintergrund: The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).
Alias Symbols: DKFZp761G1421, KIAA1938, MRD5, RASA1, RASA5, SYNGAP
Protein Interaction Partner: SAAL1, DLGAP4, GRIN1, ULK1, ULK2, MPDZ, CAMK2A, TRIP6, DLG4, GRIN2D, DLG3, KDR, PDGFRB, GRIN2B,
Protein Size: 1343

Molekulargewicht: 148 kDa

Gen-ID: 8831

NCBI Accession: NM_006772, NP_006763

UniProt: Q96PV0

Pathways: Regulation of long-term Neuronal Synaptic Plasticity