FLNC Antikörper (N-Term)

Produktnummer ABIN2789843

Produktdetails anti-FLNC Antikörper

Target: FLNC (Filamin C, gamma (FLNC))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FLNC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VGKSADFVVE AIGTEVGTLG FSIEGPSQAK IECDDKGDGS CDVRYWPTEP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FLNC. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human FLNC

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 2692 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FLNC Antikörper (ABIN2789843)

Begay, Tharp, Martin, Graw, Sinagra, Miani, Sweet, Slavov, Stafford, Zeller, Alnefaie, Rowland, Brun, Jones, Gowan, Mestroni, Garrity, Taylor: "FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy." in: JACC. Basic to translational science, Vol. 1, Issue 5, pp. 344-359, (2016) (PubMed).

Details zu FLNC

Target: FLNC (Filamin C, gamma (FLNC))

Andere Bezeichnung: FLNC (FLNC Produkte)

Synonyme: 1110055E19Rik antikoerper, ABP-280 antikoerper, ABPL antikoerper, Fln2 antikoerper, ABP280A antikoerper, ABPA antikoerper, FLN2 antikoerper, MFM5 antikoerper, MPD4 antikoerper, filamin C antikoerper, filamin C L homeolog antikoerper, filamin C, gamma antikoerper, FLNC antikoerper, flnc.L antikoerper, flnc antikoerper, Flnc antikoerper

Hintergrund: This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ABP-280, ABP280A, ABPA, ABPL, FLJ10186, FLN2
Protein Interaction Partner: RAPGEF2, TRIM63, TRIM55, XIRP1, XIRP2, SYNPO2, UBC, KCMF1, CTTNBP2NL, ANKRD28, ARFGEF2, NCAPD2, TXNL1, PSMD13, PSMD12, PSMD3, NUP88, IKBKB, FLNB, AP3S1, NPM1, IGSF8, FN1, IQCB1, TP63, VCAM1, RPS6KA2, DYNLRB1, NUP133, SAP30BP, SF3A3, SRSF9, ENO1, EEF1G, EE
Protein Size: 2692

Molekulargewicht: 296 kDa

Gen-ID: 2318

NCBI Accession: NM_001127487, NP_001120959

UniProt: Q14315